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Baby Vaccination Schedule: Complete Guide From Birth to 2 Years (Pakistan EPI)

baby care 16 min read

Baby Vaccination Schedule: Complete Guide From Birth to 2 Years (Pakistan EPI)

Newbornsy Team

Newbornsy Team

Expert Physician • March 28, 2026

Baby Vaccination Schedule: Complete Guide From Birth to 2 Years (Pakistan EPI)

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Baby vaccination schedule protects against 12 life-threatening diseases in Pakistan through EPI (Expanded Programme on Immunization). Learn complete timeline birth to 2 years: BCG/OPV/Hepatitis B at birth, Pentavalent/PCV/Rotavirus at 6/10/14 weeks, Measles-Rubella at 9 months, Typhoid at 12 months, boosters at 15 months. Includes free vs paid vaccines, where to get vaccines (BHU, RHC, DHQ, private), side effects management, missed vaccine catch-up, and addressing vaccine hesitancy in Pakistan.

Baby Vaccination Schedule: Complete Guide From Birth to 2 Years (Pakistan EPI)

Baby vaccination schedule protects against 12 life-threatening diseases in Pakistan through EPI (Expanded Programme on Immunization). Learn complete timeline birth to 2 years: BCG/OPV/Hepatitis B at birth, Pentavalent/PCV/Rotavirus at 6/10/14 weeks, Measles-Rubella at 9 months, Typhoid at 12 months, boosters at 15 months. Includes free vs paid vaccines, where to get vaccines (BHU, RHC, DHQ, private), side effects management, missed vaccine catch-up, and addressing vaccine hesitancy in Pakistan.

Quick Reference: When Are Vaccines Due?

Age Vaccines Due Protects Against
AT BIRTH • BCG
• OPV-0
• Hepatitis B-1
Tuberculosis, Polio, Hepatitis B
6 WEEKS • Pentavalent-1
• PCV-1
• OPV-1
• Rotavirus-1
Diphtheria, Tetanus, Pertussis, Hepatitis B, Hib, Pneumonia, Polio, Diarrhea
10 WEEKS • Pentavalent-2
• PCV-2
• OPV-2
• Rotavirus-2
(Same as 6 weeks - dose 2)
14 WEEKS • Pentavalent-3
• PCV-3
• OPV-3
(Same as 6 weeks - dose 3, no Rotavirus)
9 MONTHS • Measles-Rubella (MR) Measles, Rubella (German measles)
12 MONTHS • Typhoid Conjugate Vaccine (TCV) Typhoid fever
15 MONTHS • Measles-Rubella (MR-2)
• DTP Booster
Measles, Rubella, Diphtheria, Tetanus, Pertussis (booster doses)

Total visits needed: 7 visits from birth to 2 years to complete full immunization schedule.

What Is Pakistan EPI? (Expanded Programme on Immunization)

According to Federal Directorate of Immunization Pakistan:

"EPI aims to vaccinate children aged 0-15 months against 12 Vaccine Preventable Diseases (VPDs)."
— Federal Directorate of Immunization, Pakistan

The 12 diseases EPI protects against:

  1. Tuberculosis (TB)
  2. Poliomyelitis (Polio)
  3. Diphtheria
  4. Pertussis (Whooping cough)
  5. Tetanus
  6. Hepatitis B
  7. Haemophilus influenzae type b (Hib) - causes meningitis
  8. Pneumococcal disease (Pneumonia)
  9. Rotavirus diarrhea
  10. Measles
  11. Rubella (German measles)
  12. Typhoid fever

EPI in Pakistan - key facts:

  • Launched in 1978 (46 years of protecting Pakistani children)
  • ALL vaccines are FREE at government health facilities
  • Aims to immunize 3.39 million children (0-23 months) annually
  • Uses WHO pre-qualified vaccines (quality assured)
  • Available at: Basic Health Units (BHU), Rural Health Centers (RHC), District Headquarters (DHQ) hospitals, Tehsil Headquarters (THQ) hospitals, and through outreach workers

Complete Pakistan EPI Schedule: Birth to 2 Years (Detailed)

AT BIRTH (Within 24 Hours)

1. BCG (Bacille Calmette-Guérin) - Tuberculosis Vaccine

  • What it protects against: Tuberculosis (TB) - serious lung infection
  • How it's given: Injection in upper left arm
  • Important note: Leaves small scar on arm (this is normal and expected)
  • Side effects: Small bump forms, turns into blister, heals in 2-5 months leaving scar. Do NOT cover or apply cream.

2. OPV-0 (Oral Polio Vaccine - Birth Dose)

  • What it protects against: Polio (causes permanent paralysis)
  • How it's given: 2 drops by mouth
  • Why at birth: Pakistan is one of only 2 countries where polio still exists. Early protection is critical.
  • Side effects: Usually none

3. Hepatitis B-1 (Birth Dose)

  • What it protects against: Hepatitis B virus (causes liver disease)
  • How it's given: Injection in thigh
  • Why at birth: Mother may unknowingly have Hepatitis B. Birth dose protects baby immediately.
  • Side effects: Mild soreness at injection site

6 WEEKS OLD

1. Pentavalent Vaccine - Dose 1 (5-in-1 Vaccine)

  • What it contains: DTP (Diphtheria, Tetanus, Pertussis) + Hepatitis B + Hib
  • Protects against 5 diseases in single injection
  • How it's given: Injection in thigh
  • Side effects: Fever, fussiness, soreness. Normal for 1-2 days.

2. PCV-1 (Pneumococcal Conjugate Vaccine) - Dose 1

  • What it protects against: Pneumococcal bacteria (causes pneumonia, meningitis, ear infections)
  • How it's given: Injection in thigh
  • Important: Pneumonia is leading cause of death in Pakistani children under 5. This vaccine is CRITICAL.
  • Side effects: Mild fever, redness at injection site

3. OPV-1 (Oral Polio Vaccine) - Dose 1

  • How it's given: 2 drops by mouth
  • Side effects: Usually none

4. Rotavirus-1 (Oral Vaccine) - Dose 1

  • What it protects against: Rotavirus diarrhea (severe, life-threatening diarrhea in babies)
  • How it's given: Liquid by mouth
  • Introduced: 2017 in Pakistan EPI
  • Side effects: Mild diarrhea or vomiting (rare)

10 WEEKS OLD

Same vaccines as 6 weeks - Dose 2:

  • Pentavalent-2
  • PCV-2
  • OPV-2
  • Rotavirus-2

Why multiple doses: Building immunity takes several doses. Each dose strengthens protection.

14 WEEKS OLD

Final doses (Dose 3):

  • Pentavalent-3
  • PCV-3
  • OPV-3
  • Note: NO Rotavirus at 14 weeks (only 2 doses needed)

After 14 weeks: Baby has completed primary series! Next vaccine at 9 months.

9 MONTHS OLD

Measles-Rubella Vaccine (MR-1)

  • What it protects against: Measles (highly contagious, can be fatal) and Rubella (German measles)
  • How it's given: Injection in arm or thigh
  • Introduced: 2021 in Pakistan (replaced single Measles vaccine)
  • Side effects: Mild fever, rash 7-10 days after vaccine (normal immune response)
  • Important: Do NOT give before 9 months - won't work properly if given too early

12 MONTHS OLD (1 Year)

Typhoid Conjugate Vaccine (TCV)

  • What it protects against: Typhoid fever (serious bacterial infection spread through contaminated food/water)
  • How it's given: Injection in arm
  • Introduced: 2021 in Pakistan EPI (newest vaccine)
  • Why it's important: Pakistan has high burden of typhoid. Many strains are drug-resistant (XDR typhoid).
  • Side effects: Mild soreness, fever

15 MONTHS OLD (1 Year 3 Months)

Booster Doses:

  • Measles-Rubella (MR-2): Second dose for lifelong protection
  • DTP Booster: Strengthens protection against Diphtheria, Tetanus, Pertussis

Why boosters are needed: Immunity from earlier doses fades over time. Boosters restore full protection.

After 15 months: Child has completed ALL EPI vaccines! Next doses at school entry (4-6 years).

Free EPI Vaccines vs Private/Paid Vaccines in Pakistan

FREE Government EPI Vaccines

What's included (ALL FREE at government centers):

  • BCG
  • OPV (4 doses)
  • Hepatitis B (4 doses - birth + 3 in Pentavalent)
  • Pentavalent/DTP (3 doses + 1 booster)
  • PCV (3 doses)
  • Rotavirus (2 doses)
  • Measles-Rubella (2 doses)
  • Typhoid (1 dose)

Brands used in government EPI:

  • Pentavalent: Various WHO-prequalified brands
  • PCV: Synflorix (PCV-10) - protects against 10 pneumococcal types
  • Rotavirus: Rotarix (2-dose schedule)

Private/Paid Vaccines (Available at Private Clinics)

Additional vaccines NOT in government EPI:

Vaccine Protects Against Schedule Approx Cost (PKR)
MMR Measles, Mumps, Rubella 12 months, 15 months Rs. 1,500-2,500 per dose
Varicella (Chickenpox) Chickenpox 12 months, 4-6 years Rs. 3,000-4,000 per dose
Hepatitis A Hepatitis A virus 12 months, 18 months Rs. 2,000-3,000 per dose
Meningococcal Meningococcal meningitis 9 months or 12 months Rs. 3,000-5,000
Flu (Influenza) Seasonal flu 6 months onwards, yearly Rs. 1,000-1,500 per dose

Upgraded private options (same diseases, different brands):

  • Hexavalent vaccine (6-in-1): Pentavalent + IPV (Inactivated Polio Vaccine). Cost: Rs. 3,000-4,000 per dose
  • Prevenar-13 (PCV-13): Covers 13 pneumococcal types (vs government's 10 types). Cost: Rs. 4,000-5,000 per dose

Should I Get Private Vaccines?

Government EPI vaccines are SUFFICIENT for full protection. However, private vaccines offer:

  • âś… Protection against additional diseases (MMR includes Mumps, Varicella prevents chickenpox)
  • âś… Broader coverage (PCV-13 vs PCV-10, Hexavalent includes IPV)
  • âś… Convenience (fewer injections with combination vaccines)
  • ❌ Significant cost (Rs. 15,000-30,000 total for private schedule)

Bottom line: If budget allows, private vaccines add extra protection. If not, government EPI provides EXCELLENT core protection for FREE.

Where to Get Vaccines in Pakistan

1. Government/Free EPI Centers

Basic Health Units (BHU):

  • Located in rural areas, Union Councils
  • Offer ALL EPI vaccines FREE
  • Fixed vaccination days (usually 2-3 days per week)
  • Staffed by vaccinators, Lady Health Workers (LHWs)

Rural Health Centers (RHC):

  • Larger than BHUs, cover multiple Union Councils
  • Daily vaccination services
  • All EPI vaccines available FREE

District Headquarters (DHQ) & Tehsil Headquarters (THQ) Hospitals:

  • Major government hospitals in every district
  • Immunization departments with daily services
  • Walk-in vaccination (no appointment needed)
  • All EPI vaccines FREE

Outreach Vaccination:

  • Lady Health Workers (LHWs) visit homes
  • Mobile vaccination teams in remote areas
  • Check with local LHW for schedule

2. Private Clinics & Hospitals

Examples:

  • Aga Khan University Hospital (AKUH) - Karachi, Karachi
  • Shifa International Hospital - Islamabad
  • Services Hospital - Lahore
  • Local pediatric clinics

Advantages:

  • More convenient timing
  • Additional vaccines available (MMR, Varicella, Hepatitis A)
  • Upgraded vaccine options (Hexavalent, PCV-13)
  • Appointment-based (less waiting)

Cost: Rs. 500-1,500 per visit (doctor fee) + vaccine costs

How to Find Nearest EPI Center

Sehat Tahaffuz Helpline: 1166

  • FREE helpline by Federal Directorate of Immunization
  • Call to find nearest vaccination center
  • Ask about vaccine availability
  • Available nationwide

Common Vaccine Side Effects & How to Manage at Home

According to Federal Directorate of Immunization Pakistan: "Vaccines may induce mild symptoms such as localized soreness at the injection site, irritability, or a low-grade fever. These are normal and show the immune system is working."

Expected Side Effects (Normal Reactions)

Side Effect When It Happens How to Manage
Mild Fever
(100-101°F / 37.7-38.3°C)
Within 24 hours after vaccine • Give paracetamol (acetaminophen) - age-appropriate dose
• Keep baby cool (light clothing)
• Offer extra breastfeeding/fluids
• Lasts 1-2 days
Redness, Swelling at Injection Site Within 24 hours • Apply cool (not cold) compress
• Do NOT rub or massage
• Move baby's leg/arm gently
• Goes away in 2-3 days
Fussiness, Irritability Day 1-2 after vaccine • Offer extra comfort, cuddle more
• Breastfeed on demand
• Gentle rocking
• Normal activity within 24-48 hours
Mild Diarrhea
(Rotavirus vaccine)
Within 1 week • Continue breastfeeding
• Ensure hydration
• Should resolve in 2-3 days
Rash 7-10 Days Later
(Measles vaccine)
7-10 days after MR vaccine • This is NORMAL immune response
• Not contagious
• Goes away on its own
• No treatment needed

When to Call Doctor (Serious Reactions - Rare)

🚨 Call Doctor IMMEDIATELY If:

  • High fever over 102°F (38.9°C)
  • Fever lasting more than 2 days
  • Baby has seizure or fits
  • Difficulty breathing, wheezing
  • Severe swelling at injection site (larger than 2 inches)
  • Baby extremely lethargic (won't wake for feeding)
  • Severe allergic reaction (rash all over body, face swelling)

Important: Serious reactions are EXTREMELY RARE (1 in 100,000 doses). Benefits of vaccination FAR outweigh risks.

What If I Missed the Vaccination Schedule?

Don't panic! Vaccines can be caught up.

General Catch-Up Principles

  1. Start where you left off. You don't restart the entire series - just continue from where you stopped.
  2. Minimum intervals between doses:
    • Pentavalent/PCV/OPV doses: Minimum 4 weeks apart
    • Measles-Rubella doses: Minimum 4 weeks apart
  3. Age limits for certain vaccines:
    • Rotavirus: Can ONLY be given up to 24 weeks (6 months) age. After 6 months, skip it.
    • All other vaccines: No maximum age limit - can catch up at any age

Common Catch-Up Scenarios

Scenario 1: Missed 6-week vaccines, baby now 3 months old

  • Action: Start immediately with dose 1 of Pentavalent, PCV, OPV, Rotavirus
  • Give dose 2 after 4 weeks
  • Give dose 3 after another 4 weeks
  • Continue with 9-month vaccines at 9 months

Scenario 2: Missed 9-month Measles vaccine, baby now 15 months

  • Action: Give MR-1 now
  • Give MR-2 (second dose) 4 weeks later
  • Give DTP booster along with MR-2

Scenario 3: Baby 8 months old, never received ANY vaccines

  • Action: Visit EPI center or pediatrician for complete catch-up plan
  • Will need: BCG, Hepatitis B, 3 doses Pentavalent, 3 doses PCV, OPV doses, skip Rotavirus (too old)
  • Vaccinator will create custom schedule

Where to Get Catch-Up Vaccines

  • EPI centers: Will provide catch-up schedule FREE
  • Call Sehat Tahaffuz helpline: 1166 for guidance
  • Private pediatrician: Can create catch-up plan

Important: Better late than never! Even if severely delayed, catching up provides protection.

Addressing Vaccine Hesitancy in Pakistan: Common Concerns Answered

Pakistan has one of the highest rates of unvaccinated children globally. According to WHO: "Pakistan reported 1.2 million children under 1 year who missed first vaccine dose in 2017."

Common Concern 1: "Polio drops are harmful / make children sick"

FACT: Polio vaccine is SAFE. According to Federal Directorate of Immunization:

  • Over 10 BILLION doses given worldwide since 1988
  • Pakistan is one of only 2 countries where polio still paralyzes children
  • Every child needs polio vaccine to be protected
  • Side effects are extremely rare (less than 1 in 2.4 million doses)
  • NOT giving polio drops puts child at risk of permanent paralysis

Common Concern 2: "Too many vaccines at once will overwhelm baby's immune system"

FACT: Babies' immune systems can handle multiple vaccines safely.

  • Babies encounter thousands of germs daily (from air, food, environment)
  • Vaccines contain tiny amounts of weakened/killed germs
  • Combination vaccines (like Pentavalent) are SAFER than separate injections (fewer needle pokes, less pain)
  • Schedule is scientifically designed for maximum protection with minimum visits

Common Concern 3: "Vaccines cause autism"

FACT: Multiple large scientific studies prove vaccines do NOT cause autism.

  • Original study claiming link was FRAUDULENT and retracted
  • Doctor who published it lost medical license
  • Studies of millions of children show NO link between vaccines and autism
  • Autism is genetic condition that develops before birth

Common Concern 4: "Natural immunity is better than vaccine immunity"

FACT: Vaccines provide immunity WITHOUT the risk of disease complications.

  • Measles can cause brain damage and death
  • Diphtheria can cause heart failure
  • Pertussis (whooping cough) can cause babies to stop breathing
  • Getting "natural" immunity means child must survive the disease first
  • Vaccines provide protection WITHOUT the suffering

Common Concern 5: "These diseases don't exist anymore, so vaccines aren't needed"

FACT: Diseases are rare BECAUSE of vaccines. They will return if we stop vaccinating.

  • Polio still paralyzes children in Pakistan (34 cases in 2024)
  • Measles outbreaks occur in areas with low vaccination (Sindh outbreak 2023)
  • Diphtheria cases reported in KPK (2022-2023)
  • Typhoid is extremely common in Pakistan (XDR strains spreading)
  • Only vaccination keeps these diseases controlled

The Bottom Line: Complete Vaccination Protects Your Child's Life

According to Federal Directorate of Immunization Pakistan: "Immunization is believed to be the most cost-effective public health intervention. Vaccination significantly reduces childhood mortality."

Key takeaways:

  • Complete schedule: 7 visits from birth to 15 months protects against 12 life-threatening diseases
  • FREE in Pakistan: All EPI vaccines available free at BHU, RHC, DHQ hospitals
  • Critical vaccines: BCG at birth, Pentavalent at 6/10/14 weeks, PCV, Rotavirus, Measles-Rubella, Typhoid
  • Side effects: Mild and temporary (fever, soreness 1-2 days). Serious reactions extremely rare.
  • Missed vaccines: Can catch up - don't restart, continue from where you left off
  • Vaccine hesitancy: Concerns based on myths. Scientific evidence proves vaccines are safe and effective.
  • Private options: Additional vaccines (MMR, Varicella) available for extra protection

Where to start:

  1. Vaccinate baby at birth (BCG, OPV, Hepatitis B) before leaving hospital
  2. Schedule 6-week vaccines on calendar
  3. Keep immunization card safe (needed for school admission)
  4. Call Sehat Tahaffuz helpline 1166 for nearest EPI center
  5. Complete ALL doses on time for full protection

Remember: Vaccines save lives. Pakistan loses thousands of children annually to vaccine-preventable diseases. Don't let your child be one of them. Complete the EPI schedule - it's FREE, it's SAFE, and it WORKS. Your child deserves full protection. đź’‰

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Newbornsy Team
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About Newbornsy Team

Senior Medical Advisor • Pediatric Specialist

Dr. Newbornsy Team has dedicated over 15 years to pediatric care and parental education. Their research focuses on early development and child comfort during essential care routines.

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